PATHOPHYSIOLOGY OF DIABETIC POLYNEUROPATHY - METABOLIC THEORIES
Abstract:
The aim of this article is to bring into light the current metabolic theories underlying the pathophysiological changes that lead ultimately to the development of diabetic polyneuropathy. The factors that contribute to the development of diabetic polyneuropathy are not fully understood, so that multiple hypotheses were advanced. It is generally accepted as a multifactorial process. The development of clinical symptoms depends on many factors such as prolonged hyperglycaemia and other risk factors such as dyslipidaemia, hypertension, smoking, overweight, exposure to other toxic agents like alcohol. Genetic factors also play an important part.
full text article in Romanian (.RO) |
full text article in English (.EN) |