PROGNOSTIC FACTORS IN PREDICTING THE SHORT TERM RESPONSE IN THE PATIENTS WITH CARDIAC RESYNCHRONIZATION THERAPY
Abstract:
We assess the potential benefit of cardiac resynchronization therapy in the patients with normal sinus rhythm, drug refractory chronic heart failure related to dilated cardiomyopathy and prolonged QRS duration. 31 consecutive patients were included with NYHA class II (n=4), class III (n=12) or class IV (n=15) heart failure, LV ejection fraction <30%, and prolonged QRS ≥ 150 ms received biventricular pacing therapy. The 6-minute walk distance was also increased early after the pacing therapy (3 months) and improved additionally by 9 months (all P<0.05). The LV fractional shortening and ejection fraction improved progressively during the resynchronization therapy and were significantly higher than the baseline values after 3 (p<0.05) and 9 months (p<0.01). Cardiac resynchronization therapy reverses LV remodelling and improves cardiac function. The patients with longer QRS duration and longer mitral regurgitation duration are more likely to benefit from atriobiventricular stimulation.
full text article in Romanian (.RO) |
full text article in English (.EN) |