CHROMOSOMAL ABNORMALITIES IN COUPLESWITH MALFORMED STILLBIRTHS OR INFANTS
Abstract:
The paper aims to identify the type and frequency of chromosomal abnormalities in couples with malformed stillbirths or infants deceased, as well as to identify the particularities in such couples. The study was accomplished on 32 couples who had malformed stillbirths or infants deceased. Both members of the couples were investigated through medical and familial anamnesis and conventional cytogenetic analyses. For the identification of couple’s characteristics with chromosomal abnormalities, bivariate analysis was realized. In this group of patients, the overall frequency of chromosomal abnormalities was of 4.68%. The balanced chromosomal abnormalities identified were: reciprocal (n=2) and Robertsonian translocations (n=1). Bivariate analyzes revealed the statistical significant differences in male and female age, presence of spontaneous abortion and familial anamnesis positive for reproduction failure in the couples with chromosomal abnormalities.
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