ALLOGENEIC STEM CELL TRANSPLANTATION IN HODGKIN’S DISEASE STAGE IVWITH RELAPSE AFTER AUTOLOGOUS STEM CELL TRANSPLANTATION
Abstract:
We present the case of a young patient with Hodgkin disease who benefited from an allogeneic stem cell transplantation from a compatible sibling. 3 years prior the allogeneic transplant, the patient received an autologus hematopoietic stem cell transplant after which it relapsed. Upon admission in our clinic, he was in stage IVB with high fever, abdominal masses and adenopathies on both sides of the diaphragm. We administered 2 DHAP salvage courses with relatively good response, with the disappearance of the B symptoms and the decreasing of the volume of the adenopathies. Having in view the significant residual disease we decided to administer a miniBEAM protocol before the allogeneic transplantation. We present the evolution of the case, the complications and the results obtained.
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