MORPHOCLINICAL OBSERVATIONS IN COLORECTAL CARCINOMA
Abstract:
Introduction: Colorectal cancer is one of the most present neoplastic diseases of the digestive tract and requires constant study of factors that can be influenced to improve patient prognosis. Material and methods: In this study, we focused on selecting the patients who benefited from surgical treatment for colorectal tumour. Beside the clinical trial, we aimed at the immunohistochemical analysis of molecular factor (VEGF), which is involved in stimulating tumour growth. Results: Clinical trial results enrol in the margins presented by other contemporary studies on the biological factors involved and the therapeutic conduct addressed. VEGF positivity in some examined cases can be correlated with subsequent prognosis of the disease. Conclusions: In the treatment of colorectal carcinoma, surgery is extremely important and the diagnosis that involves and determines the molecular factors responsible in tumour development may allow the implementation of a treatment behaviour as accurate as possible.
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