CARDIOPULMONARY EXERCISE TESTING IN CARDIORENAL SYNDROME
Abstract:
Introduction: The cardiorenal syndrome (CRS) is a heterogeneous pathology with important prognostic significance when present. Aim of the study: In this study, we aimed at identifying some of the risk factors influencing the prognosis of CRS patients. Materials and Methods: We analyzed 85 patients with heart failure hospitalized in Monzino Cardiology Centre in Milan during a 3-month period. The glomerular filtration rate (GFR) was calculated using the MDRD equation (Modification of Diet in Renal Disease) and maximal oxygen consumption (VO2max) was measured during cardiopulmonary exercise testing. Results: VO2 max was significantly decreased correspondingly to the decrease of the GFR. Patients with a GFR <30ml/min/1, 73m2 had more major risk factors (advanced age, NYHA class 4, anemia, diabetes, BNP> 600pg/ml, VO2max <14ml/kg/min) than the patients with higher GFR. Conclusions: The presence of cardiorenal syndrome is associated with an increased incidence of major cardiovascular risk factors and a poor performance during exercise.
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