DOUBLE UROGENITAL CANCER: BLADDER AND PROSTATE CANCER – CASE REPORT
Abstract:
According to the literature, among multiple primary urogenital tumours, the association between bladder cancer and prostate cancer is less common. We present the case of a smoker male patient, 63-year-old, who in 2007 was diagnosed with high grade malignancy poorly urothelial carcinoma. He complained, in August 2011, of incomplete chronic urinary retention, dysuria, and polachiuria and prostate specific antigen (PSA) has a value of 7 ng/dl. A transurethral prostatic resection was performed. The histopathological examination of the prostate revealed prostate tissue with poorly differentiated adenocarcinoma, Gleason Score 9=4+5. Usually, the distinction of adenocarcinoma of the prostate from urothelial carcinoma of bladder can be performed on haematoxylin-eosin (HE) staining. But in this case, because both tumours are poorly differentiated, immunohistochemical tests were mandatory by applying a panel of monoclonal antibodies. The immunonohistochemical profile proved double bladder and prostate cancer. In conclusion, immunohistochemical techniques showed two distinct types of cancer located in close proximity, especially because both were poorly differentiated. Therefore, a diagnosis of cancer in urogenital area should not exclude the existence of other concomitant malignancy, especially in patients in the sixth decade of age.
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