THE ASSOCIATION BETWEEN RHEUMATOID ARTHRITIS, PERIODONTITIS AND ISCHEMIC HEART DISEASE
Abstract:
Patients with active rheumatoid arthritis (RA) have a significantly higher incidence of gum disease compared with healthy subjects, in RA patients the correlation with tooth and alveolar bone loss being demonstrated. It is interesting to study the relationship between the rheumatoid factor (RF), anticyclic citrullinated peptide antibodies (anti CCP), and Porphinomonas gingivalis (Pg), RF and anti CCP, present in RA, these being identified in the gum and in the subgingival plaque as well. The presence of gum disease increases the chance of developing heart disease, and mortality from cardiovascular damage in patients with RA, is 2 times higher compared to the general population. Based on these observations the question, whether oral infections play an important role in the pathogenesis of rheumatoid arthritis, and whether cardiovascular disease increases the risk in these patients, arises.
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