EFFECTIVENESS OF ORAL DEXTROSE GEL 40% FOR PAIN MANAGEMENT IN INFANTS DURING HEEL LANCE
Abstract:
Newborns are subject to pain during routine invasive procedures. Pain caused by blood
collection through heel lance is routinely underestimated and often untreated. The aim of this study was
to compare the effectiveness of oral Dextrose Gel 40% to actual standard of care Glucose 255 to control
infant’s pain during routine heel lance blood collection for metabolic disease screening at 72 hours of
age in healthy term neonates. In this prospective, randomised clinical trial we enrolled 100 healthy term
newborn infants at 72 hours of age, who underwent blood collection and were randomized to two
treatment groups: Glucose 25% and Dextrose 40% Gel oral. Pain was measured by the Preterm Infants
Pain Profile (PIPP Scale). Pain was significantly lower in infants in the Dextrose 40% Gel group than
those in Glucose 25% (standard of care) group. Dextrose Gel 40% is an effective pain management
method during heel lance blood collection procedure.
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