TESTOSTERONE AND 17-HIDROXIPROGESTERONE IN A BATCH OF WOMEN WITH CONGENITAL ADRENAL HYPERPLASIA WITH DELAYED DEBUT
Abstract:
Testosterone (T) is the main androgen hormone and 17-hydroxyprogesterone (17-OHP) is the most important marker of congenital adrenal hyperplasia (CAH) through deficit of 21- hydroxylasa. The purpose of the study was to establish the alteration of these two hormones in a group of women diagnosticated with the non-classic form of CAH. The study took into consideration 41 cases diagnosticated with CAH, non-classic form, through the measurement of 17-OHP and ACTH testing. Regarding testosterone, 36,6% of cases had abnormally increased values. Although 63,4% of the cases had basal 17-OHP over the normal limit, in 95% of the cases, the stimulation test was necessary in order to confirm the diagnosis.
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