DYSLIPIDAEMIA ASSOCIATEDWITH ACUTE INFECTION WITH EPSTEIN BARR VIRUS
Abstract:
The Epstein Barr virus (EBV), included in the
herpes family, determines minor clinical manifestations
or asymptomatic forms in young children, susceptible
after the disappearance of the maternal antibodies
transmitted through the placenta. Adolescents and young
adults develop different symptoms in 30-50% of the cases
and sometimes, these may take severe aspects. EBV
persistence in the body is correlated with the development
of a multitude of malignancy: lymphoproliferative
disorders, Hodgkin lymphoma, Burkitt lymphoma,
nasopharyngeal carcinoma, cerebral lymphoma in
patients with AIDS, highlighting the viral genome in the
tumour cells. We report the case of a young female
patient who was diagnosed with acute infection with
Epstein-Barr virus, who was hospitalized with persistent
fever, intense physical asthenia, abdominal pain,
lymphadenopathy, jaundice, hepatosplenomegaly. Paraclinic
investigation revealed the presence of a minimum
fluid retention in pelvis, right basal pleural effusion,
leukocytosis with lymphocytosis, low fibrinogen levels,
liver cytolysis and cholestasis, positive Waller Rose
reaction, mixed dyslipidemia, with an ameliorated lipid
profile one month after the follow up, situation less
common in specialized literature.
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