EMPHASISING THE IMAGISTIC AND BIOCHEMICAL ASPECTS FROM INTERVERTEBRAL DISKS
Abstract:
The aim of the present study was to emphasise
the correspondence between the aspect of magnetic
resonance imaging (MRI) in cases with lumbar hernia
clinically manifested, stadialized according to MRI Modic
classification and the histopathological aspect in patients
with surgical interventions on the intervertebral disks.
Material and Method. The study was performed on a
batch of 103 cases selected from the patients admitted in
the Medical Rehabilitation Clinical Hospital of the town
of Baile Felix, with the diagnosis of low back pain
accompanied or not by radiculopathy due to lumbar
hernia, between January 2008-December 2008. All the
patients were investigated by MRI. 47 intervertebral disks
were taken from the operated patients for electronic
microscopy studies, in order to determine
mucopolysaccharides and collagen in the components of
the intervertebral disk. Results. In 15.55% of the cases,
type I MRI changes were revealed, in 22.33% type II
changes, and in 62.13% type III changes. Conclusions.
Clinical manifestations of low back pain accompanied or
not by radiculopathy due to lumbar hernia had a
correspondent on MRI images, expressed by Modic in 3
classes. Electronic microscopy study made on disk
fragments obtained by discectomy revealed quantitative
and qualitative changes of all types of collagen at the
level of the 3 anatomical structures of intervertebral disk,
corresponding to the MRI changes.
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