INTRAOPERATIVE OCULAR SIDE EFFECTS OF THE ALPHA-BLOCKERS USED IN THE THERAPY OF LOWER URINARY SYNDROMES
Abstract:
The alpha-blockers are used in men to treat the
symptoms of benign prostatic hyperplasia and in women
for urinary retention. Purpose: to determine the type and
the incidence of ocular side effects during cataract
phacoemulsification. Method: prospective nonrandomized
observational study, 259 eyes of 257 patients who had
undergone phacoemulsification by the same surgeon with
the same technique; patients with traumatic cataract,
previous uveitis or glaucoma surgery were excluded.
Results: Side effects occurred in approximately 4% of the
cases; all patients were on alpha1AR-antagonist
treatment, in some cases even after a very short period of
time. These side effects lead to the intraoperative floppy
iris syndrome (IFIS). The iris features were well
controlled by using intracameral epinephrine. In one
case, iris hooks were needed. There were no major
intraoperative complications. Conclusions: All patients
with IFIS were on alpha1AR-antagonist treatment.
Intraoperative measures are available, which
significantly reduce the incidence of major complications.
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