NON-ALCOHOLIC FATTY LIVER DISEASE: CLINICO-BIOLOGICAL PARTICULARITIES
Abstract:
Non-alcoholic fatty liver disease (NAFLD) is a
disease with high frequency in the world. The main risk
factors are obesity, diabetes mellitus and the metabolic
syndrome. Other essential elements which contribute to
the etiopathology of this disease are hyperinsulinemia,
high caloric diet and genetic prevalence.(1,2) NAFLD is
included in a spectrum of liver diseases characterized
mainly by fatty macrovesicular degeneration occurring in
the absence of significant alcohol consumption under 20-
30 g pure alcohol / day or under 200g pure alcohol /
week.(1,2,3) Histopathological data have shown that fatty
liver is actually the pattern of a pathological ongoing
process, with the possibility of evolution from simple
steatosis to steatohepatitis, liver fibrosis and even nonalcoholic
liver cirrhosis.(4,5)
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