THE EFFECTS OF DIOVAN AND NEBILET TREATMENT ON SOME AMBULATORY BLOOD PRESSURE INDICES IN HYPERTENSIVE PATIENTS
Abstract:
Objective: The aim of this study is to evaluate
the effects of the treatment with the angiotensin receptor
blocker - Diovan and of the cardioselective beta-blocker –
Nebilet, on some ambulatory blood pressure indices in
patients with hypertension, grade II-III. Materials and
Methods: a prospective, clinical study was conducted on
a six month follow–up period. The hypertensive patients
were randomly assigned to either Diovan (80-160mg/day)
or Nebilet (5-10mg/day). Results: 80 patients were
enrolled in the study, 42 of them in the Diovan group and
38 in the Nebilet group. Pulse pressure significantly
decreased from baseline values in both groups, but
without significant differences between groups.
Smoothness index for both systolic and diastolic blood
pressure significantly increased in both groups but
without significant differences between treatment groups.
Conclusions: After 6 months of treatment, both Diovan
and Nebilet were efficient antihypertensive therapies by
improving pulse pressure and the smoothness index in the
hypertensive patients.
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