ORAL CANDIDOSIS PREVALENCE ON PATIENTS WITH PREMATURE OVARIAN INSUFFICIENCY
Abstract:
The oral infection with Candida is opportunistic, the pathogen agent using the diminishing of
the resistance of the organism, in order to become consensual, pathogen. Starting from the premises that
the secretion rhythm of the saliva and the salivary pH depend on the concentration of the circulating
estrogen, we intended to research on the risk factors favoring the development of the oral candidosis on
women with hyper-estrogenism. So we analyzed the quantity of saliva after the stimulation, as well as
the salivary pH on a 53 patients group with precocious ovary insufficiency, compared with a testimony
group of 50 healthy women. The patients with precocious ovarian insufficiency had an un-stimulated
salivary flux inferior to the one of the testimony group and a lower salivary pH. The oral candidosis
confirmed on the Sabouraud culture was present on 13,2 % from the patients with precocious ovarian
insufficiency and on 2% of the women from the testimony group, with a positive correlation (p=0,024)
between the presence of the oral candidosis and the premature ovarian insufficiency. It can be
mentioned, with a 99% certainty (p=0,000), the presence of the positive correlation between the
premature ovarian insufficiency and the oral candidosis prevalence. The conclusion of the research: the
oral health of the patients with precocious menopause is altered by hypo-estrogenism that attracts the
hypotrophy of the oral mucosa, diminishing the salivary pH and the salivary flux and structurally and
functionally modifying the pathologic reproduction of the species of Candida in the oral cavity.
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