CORRELATION BETWEEN THE SERUM LEVELS OF TRANSAMINASES AND THE FIBROSE STAGE OF THE LIVER IN CHRONIC HEPATITIS
Abstract:
Fibrogenic reaction is a consequence of immunological mechanisms that have developed in the
presence of the virus influencing fibrogenesis. The aim of this study is to observe whether there is any
correlation between histological changes and high ALAT and ASAT values. All patients included in our study
presented some degree of fibrosis, a fact that may be explained by the easy subjective symptomatology of the
disease and the lack of reliable tests, except liver biopsy, for the detection of fibrosis. The ASAT / ALAT report
has been <1 in all cases. According to the results we have obtained, the histological activity index may be
correlated with the degree of fibrosis, and the ASAT and ALAT serum values are significant in relation to the
degree of fibrosis; therefore they may be used for the purpose of monitoring the treatment of fibrosis
regression during therapy.
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