THE MODIFICATIONS OF THE BACTERIAL HUMAN ENDOGENOUS FLORA DURING HOSPITALISATION
Abstract:
The microbes are everywhere in the biosphere and their presence invariably affects the
environment that they are growing in. Every organism must find in its environment al of the substances
required for energy generation and cellular biosynthesis and the host cell must ultimately provide the
nutritional requirements of its resident.Bacteria that form the normal flora have a full range of symbiotic
interactions with their host and there are many more bacterial cells on the surface of a human body
(including the gastrointestinal tract) than there are human cells that make up the body.The normal flora,
as well as any “contaminating” bacteria from the environment, is all found on the body surfaces; the
blood and internal tissues are sterile. If a bacteria breaches one of these surfaces, an infection may
occur, but infection does not necessarily lead to infectious disease; other factors, such as the route of
entry, the number of infectious bacteria, and (most importantly) the status of the host defences, play a
role in determining the outcome of infection.
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