CHANGES OF OCULAR HAEMODINAMIC PARAMETERS ASSESED BY COLOUR DOPPLER IMAGING IN GLAUCOMA PROGRESSION PATIENTS
Abstract:
Purpose: to find the existence of alterations in retrobulbar hemodynamics in patients with
progressive glaucoma comparing with the patients with stable disease. Methods: 35 patients with open
angle glaucoma (POAG) were included in the study. Eye checks were carried out for 24 months at an
interval of four months which consisted in determining Tio, FO examination and computerized perimetry
to determine disease progression. Also, color Doppler ultrasound was performed and systolic velocities
were measured and enddiastolic ophthalmic artery (OA), central retinal artery (ACR) and posterior
ciliary arteries (PCA). Resistivity index was calculated automatically by the device. Results: Among the
35 patients, 9 experienced disease progression through the evolution of perimeter deficits. Compared
with patients with stable disease, patients with disease progression in the measurements showed a
significant increase in Doppler resistance index (RI) in the ophthalmic artery - averaged 0.80 (p =
0.028) and a low speed in the ophthalmic artery enddiastolic - average 2.32 cm / sec (p = 0.03).
Conclusion: In patients with primary open-angle glaucoma and progression of the disease, retrobulbar
hemodynamic parameters measurements show a significant increase in vascular resistance and a
decrease in ophthalmic artery enddiastolic velocity in ophthalmic artery.
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