THE ECOGRAPHIC MONITORIZATION OF THE THYROID GLAND DIMENSIONS AT THE PATIENTS WITH ACTIVE CHRONIC HEPATITISWITH HVC AND HVB AT THE BEGGINING AND AFTER THE THERAPY WITH PEGINTERFERON α 2A
Abstract:
Objective: The objective of this paper was the ecographic monitorisation of the thyroid gland
dimension at the patients with active chronic hepatitis with HVC and HVB during the treatment with
Peginterferon α 2A 180μg. Methods: The clinical study was effectuated on a lote of 45 patients,aged
between 18 – 65 years,from witch 25 patients with active chronic hepatitis with HVC and 20 patients
with active chronic hepatitis with HVB. The distribution on sex comprised in the lote of active chronic
hepatitis with HVC 15 female patients and 10 male patients and in the lote of those with active chronic
hepatitis with HVB 11 female patients and 9 male patients.The dimension of the thyroid gland was
established ecographically at the beggining and in the end of the therapy with Peginterferon α 2A. It has
been established a medium volume of the thyroid gland for every category of the fourth categories of
patients at the beggining and at the re-evaluation.The status of the patient regarding the thyroid
dysfunction before the beginning of the treatment wasn’t taken into consideration.The patients were
selected from the clinic and the ambulatory of the Clinic and Emergency Hospital of Sibiu. In the study
there weren't included the patients that at the beginning of the treatment presented thyroid dysfunction.
The evaluation also excluded the patients with a thyroid pathology set up during therapy.Results: The
result of the determinations was a medium significant increase with percents comprised between 11 - 20
% secondary the therapy with Interferon.Conclusion: The female patients with chronic active hepatitis
with HVC presented a percentage difference between the volumes of the thyroid gland at the beggining
and after treatment increased in contrast with the female patients with chronic active hepatitis with
HVB.For the male patients the percentage difference between the volumes of the thyroid gland was
increased in the case of patients with active chronic hepatitis with HVB in contrast with the patients with
chronic active hepatitis with HVC.
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