PRE, PERI AND POSTNATAL RISK FACTORS ASSOCIATED WITH PERVASIVE DEVELOPMENTAL DISORDERS
Abstract:
Risk factors represent a research priority regarding the cause of autism spectrum disorders
(ASD). We pursued the characterization of a series of environmental factors suspected as being risk
factors, involved in the etiopathogenesis of ASD. We conducted a clinical trial, case control, analytical,
observational, and retrospective. We included in the study 54 children diagnosed with ASD and 54
healthy children. For inventorying the risk factors, we used a set of questions about the pre/ peri and
postnatal periods. We performed statistical analysis for assessing the existing link between the disease
and the risk factor.We observed a statistically significant relationship between ASD group and the
exposure to pollutants during pregnancy, infections in the newborn period and parent’s ages. In addition
to case control type small studies, a cohort type approach is required in order to distinguish different
genetic and environmental factors involved in the pathogenesis of ASD.
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