ASSOCIATED CHRONIC LYMPHOCYTIC LEUKEMIA AND ACUTE MYELOID LEUKEMIA. CASE REPORT
Abstract:
An increased incidence of different malignancies associated to chronic lymphocytic leukemia
(CLL) has been reported and it is considered a complication of this disease. The association of CLL and
acute leukemia is a rare event described in <1% of CLL, the acute leukemia has been of both the
myeloblastic and lymphoblastic types. The coexistence of acute myeloid leukemia (AML) and CLL in the
same patient has been occasionally reported. Most of these cases have been associated with the
administration of chemotherapy or radioterapy for CLL, suggesting that the former may be a secondary
leukemia. On the other hand, CLL could precede, but could also be diagnosed at the same, or delayed
time as AML, suggesting the presence of other leukemogenic factors. We describe the development of
AML in a patient with previously diagnosed CLL.
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