POSTPUBERTAL YOLK SAC TUMOUR OF THE TESTIS. THE HISTOPATHOLOGIST’S POINT OF VIEW
Abstract:
Yolk sac tumour of testis (YSTT) is an aggressive neoplasm that resembles the allantois of the
embryo and becomes a difficult diagnosis in children, even in a pure form. We present the case of a- 16
year-old boy with a right scrotal swelling and haematocele that revealed due to microscopic
examination a hepatoid – microcystic YSTT on a small testicular biopsy. The serum alpha-feto-protein
(AFP) showed detectable levels as high as 3,7 ng/L, with negative values for β-hCG and CEA 125.
Immunohistochemistry requires AFP, SALL4, Glypican 3 and cytokeratins
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