CHARACTERISTICS OF SARS-COV-2 INFECTION IN PATIENTS WITH PROSTATE NEOPLASM: CASE REPORT
Abstract:
Oncological patients are a vulnerable group to SARS-CoV-2 infection, which is caused by a
decrease in the functionality of the immune system through its fight against cancer cells, but also
through treatment. This article aims to a better understanding of the pathogenetic mechanism by
which these events occur, in particular the connection between TMPRSS2 protein, antiandrogenic
therapy, and repeated SARS-CoV-2 infections. The deepening of the possible mechanisms underlying
the interaction between COVID-19 and prostate cancer alludes to a potential association between
SARS-CoV-2 receptors on host epithelial cells, but also to how anti-androgenic therapy influences the
course of the disease.
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