CLINICAL ASPECTS INMULTIPLE SCLEROSIS
Abstract:
The first appearance of various combinations of motor, sensory,coordination, visual, and cognitive impairments, as well as symptoms of fatigue and urinary tract dysfunction compatible with central nervous system involvement in young patients, raises the possibility of multiple sclerosis. The gradual resolution of these symptoms during a period of days to weeks further supports this diagnostic entity. Clinically isolated syndrome is the first acute clinical demyelinating event with evidence of subclinical demyelination on the brain or spinal cord MRI. Pediatric multiple sclerosis represents a particular MS subgroup with provocative diagnostic. Problems of cognitive dysfunction and psychosocial adjustment have particularly serious implications in both children and teenagers with multiple sclerosis.
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