STUDY SHOWING THE NECESSITY OF A NATIONWIDE SCREENING PROGRAMME FOR COLORECTAL CANCER IN ROMANIA
Abstract:
Neoplasia is one of the main challenges, both for the medical researcher and clinician. With increasing life expectancy worldwide, the incidence of neoplasia has also increased. WHO warns about the possible increase by 70 percent of the incidence of cancer until 2034. Our study aimed at examining the feasibility of screening for colorectal cancer prevention. During 2011-2013, we conducted a screening on a group of 1058 patients, hospitalized in the most majority. The patients were admitted by the presence of suggestive colorectal symptoms or laboratory data. The battery of tests used was: CBC, ESR, CRP, transaminases, stool examination / hemoccult test for detecting occult blood feces, total colonoscopy. We have identified 9.26 % cases of adenocarcinomas and 8.9 % high-grade dysplasia (carcinoma in situ). In 12 cases, we found large, advanced adenomas. A total of 260 subjects have been detected by the 358 total number of adenomatous polyps. Of the 358 adenomas, 18.9 % had low-grade dysplasia, 8.9 % were adenomas with severe dysplasia, of which almost 50% were adenocarcinomas with submucosal invasion. In conclusion, we consider as essential to start and sustain the long-term national programme for the early detection of colorectal cancer and the correct identification of the variables of the study (minimum age, insurance level in the non-cooperating patients for the increase of the compliance level etc.).
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