Ultrasound investigation is an easy and readily accessible method to assess liver and the biliary pathology. Due to the continuously increasing performance of the method, any information provided by this method and its interpretation in the clinical context is useful. Descriptive study on a sample of 73 patients (47 patients with ascites fluid of sinusoidal portal hypertension etiology and 26 patients with neoplastic etiology ascites). We determined the gallbladder wall thickness and its size and the possible correlations between gallbladder size and ascites ethiology. The average thickness of the wall of gallbladder in the context of cirrhosis of the liver was 5.7 mm, while peritoneal average thickness was 2.5 mm.