Restless legs syndrome (RLS) is a neurological sensorimotor disorder characterized by an urge or need to move the limbs, usually associated with abnormal sensations in the legs. These symptoms are aggravating at rest, are relieved by movement, and mainly occur in the evening and/or at night. RLS has a wide range of severity symptoms, varying from minimal complaints up to significant sleep disturbance and with a negative impact on the quality of life. The current understanding of the pathophysiology of RTS suggests an involvement of iron metabolism and dopamine dysfunction. Epidemiological studies indicate that the symptoms of RTS are present in about 5-10% of the general population. It results that there is a need to understand more about RLS and its way to manifest in medical practice