Hereditary neuropathies represent a group of inherited disorders with progressive evolution that are typically classified in hereditary motor neuropathies, hereditary motor and sensory neuropathies, and hereditary sensory and autonomic neuropathies. The objective of this study was to highlight the role of medical rehabilitation, aiming to gain maximum of functional and occupational independence in patients with different types of hereditary neuropathies. This study was conducted on 143 cases diagnosed with hereditary neuropathies, admitted in the Medical Rehabilitation Clinical Hospital “Băile Felix”, Romania. In adults, research focused on identifying the main procedures needed to increase functional independence and in children, research focused on the analysis in terms of acquiring walking independence with or without aids. Mean age of investigated children was 9.45 years, which pleads for even earlier start of medical rehabilitation. Monitoring the evolution of clinical and functional parameters revealed an improvement of activities of daily living after physical-kinetic therapy initiated early.