Natural nutrition is essential in the weight and psychomotor development of the infant. Human milk is personalized and reflects the balance between maternal diet, metabolism, transport and secretion of milk and that responds to the infant's growth and development needs. Human milk is a complex and dynamic fluid that offers nutrients, antigens, passive immunity, growth factors and bioactive compounds that can actively form and educate the immune system for infants. Artificial feeding, considered as a well-balanced alternative to natural food, has evolved from a deep understanding of how human milk changes over time. The composition from the infant formulas evolved with the improvement of knowledge about natural nutrition. It is presented a prospective study that evaluates the child aged 1-23 months, depending on the diet (natural, group I or formula, group II) with the objective of outlining a general profile of the two study groups.