GLYCOSAMINOGYCAN-BASED BIOMATERIALS USED IN WOUND HEALING
Abstract:
The following review is focused on a very important wound healing biomaterial class, i.e. glycosaminoglycans, a heteroglycan-based compound. Every biomaterial has its own advantages and disadvantages, but these disadvantages are usually surpassed by blending through different methods with various other compounds. The main advantages of glycosaminoglycans include their water solubility that allows them to maintain the wound environment moist and to absorb the wound exudate. If they are mixed with other materials they can help hemostasis, they do not adhere to the wound bed and thus prevent pain when they are removed from the injured site. They are also known to have antibacterial and antioxidant properties, and low cytotoxicity. This review underlines the benefits glycosaminoglycan application has on wound healing, including the use of several blends that enhance its characteristics.
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