IMMUNE ENCEPHALITIS: CLINICAL, PARACLINICAL AND THERAPEUTIC ASPECTS (A CLINICAL CASE)
Abstract:
Immune encephalopathies are determined by an abnormal immune response and may be caused by infection or tumor. Classical onconeuronal antibodies are revealed, which act against intracellular neuronal agents. The discovery of a new group of antibodies to the surface and synaptic neuronal antigens that mediate autoimmune encephalitis is an accomplishment of the last years and enlarges the spectrum of autoimmune disorders of the central nervous system (CNS) in encephalopathy. These disorders are clinically manifested with different symptoms of CNS injuries. Many of them are presented with signs of dysfunctions of the limbic system, may occur as a consequence of some infections, however, much of the cases have a paraneoplastic character. The symptoms may be milder without changes on clinical exams. In children, psychological disturbances or other types of neurological disorders can be diagnosed. Syndromes can be treated with immunotherapy. We are describing the case of a child with immune encephalopathy.
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