A RARE CASE OF MIXED ERYTHRODERMA (MYCOSIS FUNGOIDES AND PSORIASIS) IN A PATIENTWITHOUT SYSTEMIC ANTI-TNF THERAPY
Abstract:
Mycosis fungoides and erythrodermic psoriasis are two clinical entities whose association is
rarely cited in literature. We report a 22-year-old patient with a 5-year history of psoriasis vulgaris, who
in the last 2 years had two episodes of erythroderma which required association of systemic retinoids to
topical treatment. Lymphadenopathies, weight loss, fatigue, low grade fever and erythroderma occurred
six months prior to report. Repeated skin biopsy reconfirmed the psoriasis, but by expanded
investigations (lymph node biopsy, serological and immunological investigations) the mycosis fungoides
was diagnosed. After the first chemotherapy cycle erythrodermic appearance has improved, lymph node
masses were halved, weight curve went up (3 kg gain), but the patient refused further treatments. In
conclusion, the literature description of mixed erythroderma (psoriasis and mycosis fungoides) in a
patient without systemic anti-TNF therapy or other immunosuppressant’s is rare, like in our case.
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